A Primer on Regression Methods for Decoding cis-Regulatory Logic
نویسندگان
چکیده
منابع مشابه
A Primer on Regression Methods for Decoding cis-Regulatory Logic
Introduction Importance of cis-Regulatory Elements The rapidly emerging field of systems biology is helping us to understand the molecular determinants of phenotype on a genomic scale [1]. Cis-regulatory elements are major sequence-based determinants of biological processes in cells and tissues [2]. For instance, during transcriptional regulation, transcription factors (TFs) bind to very specif...
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ژورنال
عنوان ژورنال: PLoS Computational Biology
سال: 2009
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1000269